B cell signaling
The focus of the lab is to better understand the molecular determinants of B lymphocyte differentiation in the normal and disease state. By necessity, these studies explore the in vivo environments of the primary (bone marrow) and secondary (spleen and lymphnode) lymphoid tissues, but also extend to tertiary sites to address infection, inflammation, autoimmunity and B cell neoplasia. While model systems are essential to understand and experimentally manipulate B cell responses in vivo, studies of primary and transformed human B cells are employed whenever feasible.

I am among those who think that science has great beauty. A scientist in his laboratory is not only a technician: he is also a child placed before natural phenomena which impress him like a fairy tale.
– Marie Curie